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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL17
All Species:
17.27
Human Site:
Y486
Identified Species:
34.55
UniProt:
Q6TDP4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6TDP4
NP_938073.1
642
69874
Y486
A
T
L
D
G
N
L
Y
A
V
G
G
Y
D
S
Chimpanzee
Pan troglodytes
XP_520840
626
68231
S470
W
T
S
V
A
A
M
S
T
R
R
R
Y
V
R
Rhesus Macaque
Macaca mulatta
XP_001087862
580
62778
A425
T
L
D
G
N
L
Y
A
V
G
G
Y
D
S
S
Dog
Lupus familis
XP_546727
669
72767
Y513
A
M
L
D
G
N
L
Y
A
V
G
G
Y
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCK5
604
67393
A449
S
T
R
R
L
G
V
A
V
A
V
L
G
G
F
Rat
Rattus norvegicus
Q8K430
640
69714
Y484
A
T
L
D
G
N
L
Y
A
V
G
G
Y
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515196
722
79884
A567
S
T
R
R
L
G
V
A
V
A
V
L
G
G
F
Chicken
Gallus gallus
XP_417591
590
65056
Y434
A
T
L
E
G
N
L
Y
A
V
G
G
Y
D
S
Frog
Xenopus laevis
Q6NRH0
564
63190
Q409
W
S
M
L
G
D
M
Q
T
A
R
E
G
A
G
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
Q409
W
S
M
L
G
D
M
Q
T
A
R
E
G
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
Y467
A
V
L
G
G
F
L
Y
A
I
G
G
S
D
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794711
642
69880
K480
S
A
R
R
R
Y
V
K
V
A
A
L
G
G
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94
88.6
94.1
N.A.
45.4
97.8
N.A.
42.2
84.2
37.2
36.9
N.A.
44.5
N.A.
N.A.
52.3
Protein Similarity:
100
95
88.9
95.2
N.A.
61
98.5
N.A.
57.3
89.2
53.8
53.2
N.A.
59.3
N.A.
N.A.
70.8
P-Site Identity:
100
13.3
13.3
93.3
N.A.
6.6
100
N.A.
6.6
93.3
6.6
6.6
N.A.
60
N.A.
N.A.
0
P-Site Similarity:
100
20
13.3
93.3
N.A.
20
100
N.A.
20
100
33.3
33.3
N.A.
66.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
9
0
0
9
9
0
25
42
42
9
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
9
25
0
17
0
0
0
0
0
0
9
42
0
% D
% Glu:
0
0
0
9
0
0
0
0
0
0
0
17
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
17
% F
% Gly:
0
0
0
17
59
17
0
0
0
9
50
42
42
25
25
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
9
42
17
17
9
42
0
0
0
0
25
0
0
0
% L
% Met:
0
9
17
0
0
0
25
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
34
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% Q
% Arg:
0
0
25
25
9
0
0
0
0
9
25
9
0
0
9
% R
% Ser:
25
17
9
0
0
0
0
9
0
0
0
0
9
9
42
% S
% Thr:
9
50
0
0
0
0
0
0
25
0
0
0
0
0
0
% T
% Val:
0
9
0
9
0
0
25
0
34
34
17
0
0
9
0
% V
% Trp:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
9
42
0
0
0
9
42
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _